Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | STK25 | O00506 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20801509 | 0.85 | TLR8 (0.63) | TLR8TLR7HPGDMAPK1 | |
| SCHEMBL23813762 | 0.84 | TLR8 (0.56) | TLR8TLR7HPGDMAPK1CSF1R | |
| SCHEMBL20647672 | 0.79 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL19416362 | 0.77 | TLR8 (0.57) | TLR8TLR7HPGDMAPK1CSF1R | |
| SCHEMBL1237420 | 0.77 | TLR8 (0.50) | TLR8TLR7HPGDMAPK1STK25 | |
| SCHEMBL1802374 | 0.76 | TLR8 (0.73) | TLR8TLR7HPGDMAPK1 | |
| SCHEMBL24860058 | 0.76 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL1237666 | 0.75 | TLR8 (0.72) | TLR8TLR7HPGDMAPK1CSF1R | |
| SCHEMBL23421314 | 0.75 | TLR8 (0.61) | TLR8TLR7 | |
| SCHEMBL23421924 | 0.75 | TLR8 (0.66) | TLR8TLR7HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11547761-B1 | Antibody adjuvant conjugates | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-01-10 | — | — | US | disclosed |
| US-10675358-B2 | Antibody adjuvant conjugates | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190076547-A1 | ANTIBODY ADJUVANT CONJUGATES | BOLT BIOTHERAPEUTICS, INC. | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10675358-B2 | Antibody adjuvant conjugates | FCGR1A, FCGR3B, FCGR2A | TLR8 56/4885TLR7 58/4885HPGD 2439/4885 |
| US-20190076547-A1 | ANTIBODY ADJUVANT CONJUGATES | FCGR1A, FCGR3B, FCGR2A | TLR8 59/4885TLR7 57/4885HPGD 2255/4885 |
| US-11547761-B1 | Antibody adjuvant conjugates | FCGR1A, FCGR3B, FCGR2A | TLR8 56/4885TLR7 58/4885HPGD 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.