Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ABL2 | P42684 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933162 | 1.00 | CASP3 (0.40) | CASP3PIN1ADH1AKITFLT1 | |
| SCHEMBL16933097 | 0.92 | CASP3 (0.37) | CASP3PIN1ADH1AKITFLT1 | |
| SCHEMBL21297105 | 0.91 | CASP3 (0.39) | CASP3PIN1ADH1AKITFLT1 | |
| SCHEMBL16933008 | 0.88 | CASP3 (0.35) | CASP3PIN1XIAPELANEFDFT1 | |
| SCHEMBL16933180 | 0.88 | CASP3 (0.34) | CASP3PIN1ADH1AKITFLT1 | |
| SCHEMBL16933070 | 0.86 | BACE1 (0.37) | CASP3PIN1ADH1AKITFLT1 | |
| SCHEMBL21559296 | 0.86 | CASP3 (0.34) | CASP3ELANE | |
| SCHEMBL16942085 | 0.86 | CASP3 (0.34) | CASP3ELANE | |
| SCHEMBL21234810 | 0.86 | CASP3 (0.38) | CASP3PIN1ADH1AKITFLT1 | |
| SCHEMBL18064565 | 0.85 | ADH1A (0.38) | CASP3PIN1ADH1AKITFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521292-A1 | BIFUNCTIONAL CYTOTOXIC AGENTS | Pfizer Inc (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-3099692-B1 | BIFUNCTIONAL CYTOTOXIC AGENTS | PFIZER (US) | 2019-03-13 | — | — | EP | disclosed |