Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 9/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21955313 | 0.86 | BRD4 (0.34) | ALKBH5ARPGRATAD2HDAC6 | |
| SCHEMBL24018688 | 0.82 | HDAC6 (0.33) | ARPGRNR3C1NR3C2ATAD2 | |
| SCHEMBL15549616 | 0.78 | ALKBH5 (0.37) | ALKBH5ARPGRNR3C1NR3C2 | |
| SCHEMBL27304728 | 0.78 | BAZ2B (0.39) | ARHDAC6NOTUMRECQLBAZ2B | |
| SCHEMBL17589209 | 0.75 | BRD4 (0.35) | ATAD2BAZ2BBAZ2ACREBBP | |
| SCHEMBL13481160 | 0.75 | ATAD2 (0.39) | ATAD2BAZ2BBAZ2ACREBBP | |
| SCHEMBL20906890 | 0.75 | NOTUM (0.38) | ARPGRNR3C1NR3C2ATAD2 | |
| SCHEMBL21475934 | 0.74 | MAP2K2 (0.39) | ATAD2BAZ2BBAZ2ACREBBP | |
| SCHEMBL20605804 | 0.73 | MAP2K2 (0.48) | ALKBH5NOTUMRECQLBAZ2BBAZ2A | |
| SCHEMBL20605182 | 0.72 | MAP2K1 (0.48) | RECQLBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050016-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2024-03-07 | — | — | WO | disclosed |
| EP-3423451-B1 | INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING | PROPELLON THERAPEUTICS INC (CA) | 2022-08-17 | — | — | EP | disclosed |
| WO-2019046944-A1 | INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING | Propellon Therapeutics Inc. (CA) | 2019-03-14 | — | — | WO | disclosed |