SCHEMBL2080342

SCHEMBL2080342

Oc1cc(-c2ccccc2-c2ccccc2)c(O)cc1-c1ccccc1-c1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.75
ALDH1A1 P00352 4/20 0.64
HSD17B10 Q99714 2/20 0.64
HPGD P15428 2/20 0.64
BCL2L1 Q07817 1/20 0.64
ALOX5 P09917 2/20 0.56
APP P05067 1/20 0.52
ABL1 P00519 1/20 0.48
ABCB1 P08183 1/20 0.48
BCR P11274 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
BCL2 P10415 1/20 0.46
MCL1 Q07820 1/20 0.46
PDE4B Q07343 2/20 0.46
BRD4 O60885 1/20 0.46
NR1I2 O75469 1/20 0.46
SMARCA2 P51531 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1754202 0.86 BACE1 (1.00) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL1754470 0.84 ALOX5 (0.63) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29750558 0.84 ALDH1A1 (0.80) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29399199 0.84 ALDH1A1 (0.80) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL619315 0.84 ALDH1A1 (0.80) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL28137248 0.83 BACE1 (0.83) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL30332559 0.83 ALDH1A1 (0.58) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL192419 0.83 ALDH1A1 (0.58) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29352295 0.83 ALDH1A1 (0.58) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL29414264 0.83 ALDH1A1 (0.58) BACE1ALDH1A1HSD17B10HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163864-B2 Sulfonated polyarylene compounds, membrane material made therefrom, method for the production thereof and use LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2012-04-24 US claimed
US-20110172317-A1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF AND USE LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2011-07-14 US claimed
EP-2046491-B1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF, AND USE LEIBNIZ INST POLYMERFORSCHUNG (DE) 2010-05-12 EP claimed
US-8163864-B2 Sulfonated polyarylene compounds, membrane material made therefrom, method for the production thereof and use LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2012-04-24 US disclosed
US-20110172317-A1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF AND USE LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2011-07-14 US disclosed
EP-2046491-B1 SULFONATED POLYARYLENE COMPOUNDS, MEMBRANE MATERIAL MADE THEREFROM, METHOD FOR THE PRODUCTION THEREOF, AND USE LEIBNIZ INST POLYMERFORSCHUNG (DE) 2010-05-12 EP disclosed