Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123212 | 0.79 | GSK3A (0.40) | GSK3AGSK3BCASP3HTTMAPK1 | |
| SCHEMBL20804233 | 0.68 | MGLL (0.42) | GSK3AGSK3BMGLLPTGS1PTGS2 | |
| SCHEMBL17123178 | 0.68 | PTGS1 (0.50) | GSK3AGSK3BMGLLPTGS1PTGS2 | |
| SCHEMBL3384174 | 0.66 | GSK3A (1.00) | GSK3AGSK3BMGLLCMA1CASP3 | |
| SCHEMBL13486597 | 0.66 | GSK3A (0.58) | GSK3AGSK3BPOLBMAPK1ALDH1A1 | |
| SCHEMBL11432701 | 0.63 | CA1 (0.58) | MAPK1ALDH1A1 | |
| SCHEMBL17123192 | 0.63 | GSK3A (0.66) | GSK3AGSK3BMGLLCMA1CASP3 | |
| SCHEMBL15694366 | 0.60 | GSK3A (0.60) | GSK3AGSK3BMGLLCMA1CASP3 | |
| SCHEMBL4746479 | 0.59 | KDM4E (0.50) | GSK3AGSK3BMGLLPTGS1PTGS2 | |
| SCHEMBL3381344 | 0.58 | GSK3A (1.00) | GSK3AGSK3BMGLLCMA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089962-B1 | RADIOIODINATED COMPOUNDS | NUTECH VENTURES (US) | 2019-03-13 | — | — | EP | disclosed |