Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17123178 | 0.79 | PTGS1 (0.50) | MGLLFAAHPTGS1PTGS2GSK3A | |
| SCHEMBL20047130 | 0.73 | RIPK1 (0.34) | MAPTSMN1; SMN2P2RX7 | |
| SCHEMBL4746479 | 0.71 | KDM4E (0.50) | MGLLFAAHPTGS1PTGS2GSK3A | |
| SCHEMBL20804327 | 0.69 | MGLL (0.52) | MGLLFAAHPTGS1PTGS2GSK3A | |
| SCHEMBL20804359 | 0.68 | GSK3A (0.47) | MGLLPTGS1PTGS2GSK3AGSK3B | |
| SCHEMBL16041142 | 0.67 | — | — | |
| SCHEMBL19083122 | 0.67 | LOXL2 (0.38) | — | |
| SCHEMBL16040258 | 0.67 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL19098546 | 0.67 | MEN1 (0.30) | — | |
| SCHEMBL2785687 | 0.66 | PTGS1 (0.73) | MGLLFAAHPTGS1PTGS2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3089962-B1 | RADIOIODINATED COMPOUNDS | NUTECH VENTURES (US) | 2019-03-13 | — | — | EP | disclosed |