Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20798131 | 0.88 | AR (0.48) | ARIRAK4 | |
| SCHEMBL16893979 | 0.82 | AR (0.44) | ARIRAK4 | |
| SCHEMBL20804978 | 0.79 | AR (0.44) | ARBRD4CREBBP | |
| SCHEMBL9030857 | 0.76 | AR (0.43) | AR | |
| SCHEMBL9030851 | 0.76 | AR (0.43) | AR | |
| SCHEMBL9035064 | 0.75 | AR (0.43) | AR | |
| SCHEMBL9035075 | 0.75 | AR (0.43) | AR | |
| SCHEMBL16893984 | 0.74 | AR (0.39) | AR | |
| SCHEMBL3885063 | 0.72 | ALDH1A1 (0.50) | ARBRD4CREBBP | |
| SCHEMBL9845271 | 0.72 | AR (0.41) | ARBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019050988-A1 | VASOPRESSIN RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO | BLACKTHORN THERAPEUTICS, INC. (US) | 2019-03-14 | — | — | WO | disclosed |