Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2080575 | 1.00 | MRGPRX1 (0.40) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL12778411 | 0.91 | MRGPRX1 (0.41) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL12778532 | 0.91 | MRGPRX1 (0.37) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL12778514 | 0.89 | CYP3A4 (0.39) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL2077137 | 0.88 | PTGS1 (0.40) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL12778765 | 0.88 | MRGPRX1 (0.38) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL2077135 | 0.88 | PTGS1 (0.40) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL12778518 | 0.87 | MRGPRX1 (0.35) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL12778516 | 0.87 | PTGS1 (0.35) | MRGPRX1PTGS1PTGS2CA2CCR9 | |
| SCHEMBL12778502 | 0.87 | CCR9 (0.39) | MRGPRX1CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |
| US-7906538-B2 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2011-03-15 | — | — | US | disclosed |
| US-20080262048-A1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2008-10-23 | — | — | US | disclosed |
| US-20080262048-A1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2008-10-23 | — | — | US | disclosed |
| EP-1799636-B1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING PLOUGH LTD (CH) | 2008-08-27 | — | — | EP | disclosed |
| US-7312248-B2 | Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312248-B2 | Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312248-B2 | Control of parasites in animals by the use of novel trifluoromethanesulfonanilide oxime ether derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2007-12-25 | — | — | US | disclosed |
| US-20060063841-A1 | Parasiticides; nematocides; crop protection | SCHERING-PLOUGH LTD. (CH) | 2006-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063841-A1 | Parasiticides; nematocides; crop protection | TRHDE, DDT, EPHX1 | MRGPRX1 1347/4885PTGS1 1332/4885PTGS2 1406/4885 |
| US-20080262048-A1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | TRHDE, EPX, EPHX1 | MRGPRX1 1470/4885PTGS1 1610/4885PTGS2 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.