⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17545277 | 0.85 | ALDH1A1 (0.36) | — | |
| SCHEMBL28465687 | 0.80 | LCK (0.44) | — | |
| SCHEMBL29633207 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL7519796 | 0.77 | — | — | |
| SCHEMBL55902 | 0.77 | — | — | |
| SCHEMBL7519715 | 0.77 | — | — | |
| SCHEMBL971093 | 0.76 | — | — | |
| SCHEMBL27729662 | 0.76 | — | — | |
| SCHEMBL2082092 | 0.74 | — | — | |
| SCHEMBL7068407 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101307143-A | Organic-inorganic composite lamellar compound with regular arrangement bromium and method for preparing same | UNIV SHANGHAI (CN) | 2008-11-19 | — | — | CN | claimed |
| US-20240116921-A1 | LACTAM (HETERO)ARYLFUSEDPYRIMIDINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN INC. | 2024-04-11 | — | — | US | disclosed |
| EP-4267137-A1 | LACTAM (HETERO)ARYLFUSEDPYRIMIDINE DERIVATIVES AS INHIBITORS OF ERBB2 | Enliven Inc. (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022140769-A1 | LACTAM (HETERO)ARYLFUSEDPYRIMIDINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022140769-A1 | LACTAM (HETERO)ARYLFUSEDPYRIMIDINE DERIVATIVES AS INHIBITORS OF ERBB2 | ENLIVEN THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| EP-3585775-B1 | AZETIDINE COMPOUNDS AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS | SANOFI SA (FR) | 2022-04-06 | — | — | EP | disclosed |
| US-10392366-B2 | Azetidine compounds as GPR119 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders | SANOFI (FR) | 2019-08-27 | — | — | US | disclosed |
| EP-3126336-B1 | SUBSTITUTED FUSED HETEROCYCLES AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS | SANOFI SA (FR) | 2018-12-05 | — | — | EP | disclosed |
| WO-2018153849-A1 | AZETIDINE COMPOUNDS AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS | SANOFI (FR) | 2018-08-30 | — | — | WO | disclosed |
| US-20180237419-A1 | AZETIDINE COMPOUNDS AS GRP119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY, DYSLIPIDEMIA AND RELATED DISORDERS | SANOFI (FR) | 2018-08-23 | — | — | US | disclosed |
| CN-1821226-A | Antipicornaviral compounds, their preparation and use | AGOURON PHARMA (US) | 2006-08-23 | — | — | CN | disclosed |
| WO-2006068276-A1 | HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR | SHOWA DENKO K.K. (JP) | 2006-06-29 | — | — | WO | disclosed |
| CN-1198838-C | Anti-small RNA virus compound and preparation method and application thereof | AGOURON PHARMA (US) | 2005-04-27 | — | — | CN | disclosed |
| CN-1311793-A | Anti-small RNA virus compound and preparation method and application thereof | AGOURON PHARMA (US) | 2001-09-05 | — | — | CN | disclosed |
| US-5112980-A | Intermediates for herbicides | MONSANTO COMPANY (US) | 1992-05-12 | — | — | US | disclosed |
| EP-0435844-A1 | Substituted pyridine compounds | MONSANTO COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| US-4196124-A | ANTIOBESITY AGENTS | SCHERING CORPORATION (US) | 1980-04-01 | — | — | US | disclosed |
| US-4173566-A | CHEMICAL INTERMEDIATE FOR AN ANTIOBESITY AGENT | SCHERING CORPORATION (US) | 1979-11-06 | — | — | US | disclosed |
| US-4140780-A | ANTIOBESITY AGENTS | SCHERING CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |
| US-4052383-A | ANTIOBESITY | SCHERING CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |