SCHEMBL208060

SCHEMBL208060

O=C(O)C(=O)Nc1ccc(Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.63
PTPN11 Q06124 2/20 0.61
PTPN1 P18031 1/20 0.61
NPC1 O15118 2/20 0.59
ALDH1A1 P00352 2/20 0.55
GPR35 Q9HC97 1/20 0.54
TSHR P16473 1/20 0.53
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
POLB P06746 1/20 0.52
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1504319 0.98 CYP19A1 (0.61) CYP19A1PTPN11PTPN1NPC1ALDH1A1
SCHEMBL21568080 0.88 NPC1 (0.67) NPC1ALDH1A1TSHRKMT2AMEN1
SCHEMBL10495628 0.88 PTPN11 (0.74) CYP19A1PTPN11PTPN1GPR35KMT2A
Lithium Ion SCHEMBL1504314 0.83 NPC1 (0.55) CYP19A1NPC1ALDH1A1TSHRKMT2A
SCHEMBL1507740 0.81 NPC1 (0.64) NPC1ALDH1A1TSHRKMT2AMEN1
SCHEMBL5433635 0.80 ALDH1A1 (0.59) CYP19A1NPC1ALDH1A1TSHRKMT2A
SCHEMBL672629 0.80 NPC1 (0.69) NPC1ALDH1A1TSHRKMT2AMEN1
SCHEMBL6394183 0.79 ALDH1A1 (0.63) CYP19A1PTPN11PTPN1ALDH1A1GPR35
SCHEMBL9378918 0.78 ALDH1A1 (0.68) NPC1ALDH1A1TSHRKMT2AMEN1
SCHEMBL10718716 0.78 NPC1 (0.55) NPC1ALDH1A1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119948005-A Method for synthesizing methoxy substituted benzaldehyde compound 先正达农作物保护股份公司 2025-05-06 CN claimed
EP-4608796-A1 PROCESS FOR THE SYNTHESIS OF METHOXY SUBSTITUTED BENZALDEHYDE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-09-03 EP disclosed
CN-119948005-A Method for synthesizing methoxy substituted benzaldehyde compound 先正达农作物保护股份公司 2025-05-06 CN disclosed
WO-2024089225-A1 PROCESS FOR THE SYNTHESIS OF METHOXY SUBSTITUTED BENZALDEHYDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-05-02 WO disclosed
CN-115403519-B Synthesis method of N-substituted isonicotinamide compound driven by visible light 河南师范大学 2024-03-01 CN disclosed
CN-115385858-B Photocatalytic preparation method of 2-phenyl-2H-indazole-3-carboxamide compound 河南师范大学 2024-03-01 CN disclosed
CN-114728917-B Oxamide derivative, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2023-12-08 CN disclosed
CN-114728917-A Oxamide derivative, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2022-07-08 CN disclosed
WO-2021110076-A1 OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE 深圳信立泰药业股份有限公司 2021-06-10 WO disclosed
US-20200352931-A1 OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE Phenex Discovery Verwaltungs-GmbH (DE) 2020-11-12 US disclosed
CN-1745071-A Novel ethylenediamine derivative DAIICHI SEIYAKU CO (JP) 2006-03-08 CN disclosed
US-20050245565-A1 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-11-03 US disclosed
EP-1577301-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
EP-1577302-A1 NOVEL ETHYLENEDIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-09-21 EP disclosed
US-20050119486-A1 Diamine derivatives DAIICHI SANKYO COMPANY, LIMITED (JP) 2005-06-02 US disclosed
US-20050020645-A1 Diamine derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2005-01-27 US disclosed
EP-1415992-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-05-06 EP disclosed
EP-1405852-A1 DIAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-07 EP disclosed
EP-0086746-B1 PHENYLAMINO-OXO-ACETIC ACIDS AND THEIR ESTERS AS HERBICIDAL ANTIDOTES FOR THE PROTECTION OF CULTIVATED PLANTS CIBA-GEIGY AG (CH) 1986-07-30 EP disclosed
US-4191840-A Oxamic acid derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1980-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200352931-A1 OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE IDO1, IDO2, INMT CYP19A1 626/4885PTPN11 1995/4885PTPN1 1172/4885
US-20050020645-A1 Diamine derivatives C9, C1S, C1R CYP19A1 3110/4885PTPN11 4663/4885PTPN1 4702/4885
US-20050245565-A1 Diamine derivatives C9, C1S, C1R CYP19A1 3110/4885PTPN11 4663/4885PTPN1 4702/4885
US-20050119486-A1 Diamine derivatives C9, C1S, C1R CYP19A1 3110/4885PTPN11 4663/4885PTPN1 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.