Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.51 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920765 | 0.90 | PDK2 (0.50) | PDK2S100A4AKR1B1AKR1A1PGR | |
| SCHEMBL20806334 | 0.81 | PDK2 (0.43) | PDK2PGR | |
| SCHEMBL1921508 | 0.80 | PDK2 (0.47) | PDK2S100A4AKR1B1AKR1A1HTR2C | |
| SCHEMBL28199301 | 0.80 | PDK2 (0.40) | PDK2S100A4OPRK1 | |
| SCHEMBL20806435 | 0.78 | PDK2 (0.39) | PDK2PGR | |
| SCHEMBL20806340 | 0.77 | PDK2 (0.56) | PDK2S100A4AKR1B1AKR1A1PTPN1 | |
| SCHEMBL19849937 | 0.77 | PDK2 (0.59) | PDK2S100A4AKR1B1AKR1A1PTPN1 | |
| SCHEMBL29800749 | 0.76 | PDK2 (0.62) | PDK2S100A4AKR1B1AKR1A1PTPN1 | |
| SCHEMBL12685311 | 0.76 | PDK2 (0.62) | PDK2S100A4AKR1B1AKR1A1PTPN1 | |
| SCHEMBL26852283 | 0.76 | PDK2 (0.56) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200283386-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-09-10 | — | — | US | disclosed |
| WO-2019048443-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283386-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, GPX1, SOD1 | PDK2 461/4885S100A4 392/4885AKR1B1 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.