Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2416401 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ABCB1MAOB | |
| SCHEMBL2416575 | 0.87 | LTA4H (0.43) | LTA4HMAPK14ABCB1DHFRDCPS | |
| SCHEMBL14818150 | 0.81 | — | — | |
| SCHEMBL621261 | 0.80 | ABCB1 (0.48) | HTTSMN1; SMN2ABCB1MAOB | |
| SCHEMBL620136 | 0.80 | TXNRD1 (0.39) | — | |
| SCHEMBL14818205 | 0.78 | — | — | |
| SCHEMBL2417953 | 0.77 | CYP1A2 (0.43) | — | |
| SCHEMBL20806643 | 0.77 | FFAR1 (0.32) | DHFR | |
| SCHEMBL621634 | 0.77 | IDO1 (0.41) | ABCB1 | |
| SCHEMBL12322051 | 0.76 | KCNA3 (0.41) | NPC1RAB9ASMN1; SMN2DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573559-B1 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX INC (US) | 2019-03-13 | — | — | EP | disclosed |