Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20808953 | 0.86 | TSHR (0.46) | TSHRALDH1A1TRPA1S1PR2L3MBTL1 | |
| SCHEMBL21025167 | 0.84 | TSHR (0.45) | TSHRALDH1A1TRPA1S1PR2L3MBTL1 | |
| SCHEMBL10085584 | 0.74 | HSD17B10 (0.53) | ALDH1A1MAPTTP53LMNAPOLB | |
| SCHEMBL5987420 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL20809222 | 0.73 | GRM4 (0.40) | ALDH1A1MAPTTP53HDAC1HDAC11 | |
| SCHEMBL10085091 | 0.71 | POLB (0.48) | ALDH1A1L3MBTL1POLBTHRB | |
| SCHEMBL10086153 | 0.71 | PARG (0.59) | TP53 | |
| SCHEMBL20808952 | 0.69 | EGLN1 (0.45) | TSHRALDH1A1TRPA1HDAC1HDAC8 | |
| SCHEMBL20786948 | 0.68 | KDM4E (0.54) | TSHRALDH1A1L3MBTL1TP53LMNA | |
| SCHEMBL16923630 | 0.68 | MARK4 (0.48) | TSHRMAPTCNR2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3453707-B1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2022-02-16 | — | — | EP | disclosed |
| EP-3453707-A1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2019-03-13 | — | — | EP | disclosed |