Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13560165 | 0.84 | ALDH1A1 (0.41) | ALDH1A1ATMGAAHTTL3MBTL1 | |
| SCHEMBL20809146 | 0.82 | CA1 (0.34) | — | |
| SCHEMBL14744058 | 0.81 | TP53 (0.35) | ALDH1A1ATMTDP1GAAPAX8 | |
| SCHEMBL4512108 | 0.81 | GAA (0.43) | ALDH1A1ATMGAA | |
| SCHEMBL16977614 | 0.80 | ALDH1A1 (0.34) | ALDH1A1ATM | |
| SCHEMBL24914366 | 0.78 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL4486230 | 0.78 | ALDH1A1 (0.47) | ALDH1A1ATMTDP1KDM4ENPC1 | |
| SCHEMBL21025012 | 0.77 | ALDH1A1 (0.36) | ALDH1A1ATM | |
| SCHEMBL15493077 | 0.77 | ALDH1A1 (0.33) | ALDH1A1ATMTDP1 | |
| SCHEMBL26091337 | 0.74 | BRD4 (0.38) | ALDH1A1ATMTDP1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3453707-B1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2022-02-16 | — | — | EP | disclosed |
| EP-3453707-A1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2019-03-13 | — | — | EP | disclosed |