SCHEMBL24914366

SCHEMBL24914366

CCCC1CN(S(=O)(=O)C2CC2)C1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
MMP1 P03956 1/20 0.30
MMP7 P09237 1/20 0.30
MMP12 P39900 1/20 0.30
ECE1 P42892 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4512106 0.83 CYP1A2 (0.36) ALDH1A1
SCHEMBL23564478 0.83 KAT5 (0.33)
SCHEMBL20809149 0.78 ALDH1A1 (0.35) ALDH1A1
SCHEMBL20809146 0.78 CA1 (0.34)
SCHEMBL24448812 0.75 THRA (0.32) ALDH1A1
SCHEMBL23126837 0.73
SCHEMBL20706357 0.73 ALDH1A1 (0.38) ALDH1A1
SCHEMBL23564481 0.73 ALDH1A1 (0.38) ALDH1A1
SCHEMBL13560165 0.72 ALDH1A1 (0.41) ALDH1A1
SCHEMBL4486225 0.71 CYP1A2 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230019236-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF CALICO LIFE SCIENCES LLC (US) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019236-A1 PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF PTPN1, PTPN2, PTPN18 ALDH1A1 3671/4885MMP1 3548/4885MMP7 3804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.