SCHEMBL2080936

SCHEMBL2080936

COC(=O)CCC(C(=O)OO)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
SLC1A1 P43005 1/20 0.38
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 3/20 0.33
CA12 O43570 2/20 0.33
CA14 Q9ULX7 2/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
USP2 O75604 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13764530 0.79 TSHR (0.44) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL9186078 0.78 TSHR (0.32) TSHR
SCHEMBL911189 0.76 CA2 (0.36) TSHRLMNACA12CA14HSD17B10
SCHEMBL736105 0.75 DGKA (0.35) TSHRKMT2AMEN1LMNAKDM4E
SCHEMBL8400128 0.75 CA1 (0.31) CA1CA2GAACA7
SCHEMBL9244038 0.74 TSHR (0.52) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL373122 0.73 CA2 (0.46) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL11783553 0.73
SCHEMBL3883597 0.72
SCHEMBL16329096 0.72 TSHR (0.50) TSHRSLC1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
US-9431172-B2 Biaxially oriented electrical insulating film BOREALIS TECHNOLOGY OY (FI) 2016-08-30 US disclosed
US-8163845-B2 Biaxially oriented electrical insulating film TREOFAN GERMANY GMBH & CO. KG (DE) 2012-04-24 US disclosed
US-20100047544-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2010-02-25 US disclosed
US-20100003489-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2010-01-07 US disclosed
WO-2008034694-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2008-03-27 WO disclosed