Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.47 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20810289 | 0.87 | SPHK2 (0.59) | PPARAPPARGSPHK2SPHK1SMN1; SMN2 | |
| SCHEMBL20810562 | 0.87 | SPHK2 (0.54) | PPARAPPARGSPHK2SPHK1SMN1; SMN2 | |
| SCHEMBL20810326 | 0.84 | ALOX5 (0.46) | PPARGSPHK2SPHK1SMN1; SMN2PDE5A | |
| SCHEMBL18020999 | 0.84 | ALOX5 (0.46) | PPARGSPHK2SPHK1SMN1; SMN2PDE5A | |
| SCHEMBL20810487 | 0.84 | ALOX5 (0.46) | PPARGSPHK2SPHK1SMN1; SMN2PDE5A | |
| SCHEMBL8884118 | 0.83 | RARB (0.59) | ALDH1A1 | |
| SCHEMBL9215324 | 0.83 | RARB (0.59) | ALDH1A1 | |
| SCHEMBL15174533 | 0.83 | SPHK2 (0.64) | PPARAPPARGSPHK2SPHK1SMN1; SMN2 | |
| SCHEMBL15173985 | 0.83 | SPHK2 (0.64) | PPARAPPARGSPHK2SPHK1SMN1; SMN2 | |
| SCHEMBL29013699 | 0.83 | SMPD1 (0.67) | PPARAPPARGSPHK2SPHK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3077369-B1 | BENZAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF MUSCULAR DISORDERS AND PAIN AND FOR CONTROLLING SPASTICITY AND TREMORS | UCL BUSINESS PLC (GB) | 2019-03-13 | — | — | EP | disclosed |