Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | RARA | P10276 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.58 |
| ▸ | PLK1 | P53350 | 4/20 | 0.58 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884118 | 1.00 | RARB (0.59) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL15723430 | 0.90 | RARB (0.65) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL8883017 | 0.88 | THRA (0.63) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL28562555 | 0.86 | THRA (0.64) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL8947232 | 0.85 | PLK1 (0.55) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL12638341 | 0.85 | SPHK1 (0.57) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL15174084 | 0.85 | PLK1 (0.55) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL9491031 | 0.84 | L3MBTL1 (0.71) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL13569647 | 0.84 | SPHK1 (0.63) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL13754056 | 0.84 | PLK1 (0.65) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499521-B1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0499521-A1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-08-19 | — | — | EP | disclosed |