Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 6/20 | 0.76 |
| ▸ | IDO1 | P14902 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20811039 | 0.92 | NQO1 (0.76) | NQO1IDO1MAPTMEN1RAB9A | |
| SCHEMBL23457125 | 0.90 | NQO1 (0.73) | NQO1IDO1 | |
| SCHEMBL18791172 | 0.87 | NQO1 (1.00) | NQO1IDO1MAPTPTPN1CDC25A | |
| SCHEMBL20811501 | 0.80 | NQO1 (0.59) | NQO1IDO1MAPTMEN1NPC1 | |
| SCHEMBL23406759 | 0.80 | NQO1 (0.59) | NQO1IDO1MAPTMEN1NPC1 | |
| SCHEMBL18791169 | 0.79 | NQO1 (1.00) | NQO1IDO1MAPTMEN1NPC1 | |
| SCHEMBL18791098 | 0.79 | NQO1 (0.67) | NQO1IDO1 | |
| SCHEMBL18791168 | 0.78 | NQO1 (1.00) | NQO1IDO1MAPTMEN1HTT | |
| SCHEMBL103949 | 0.74 | IDO1 (0.53) | NQO1IDO1MAPTMEN1RAB9A | |
| SCHEMBL20811248 | 0.73 | IDO1 (0.59) | NQO1IDO1MAPTMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019050422-A1 | 5-LIPOXYGENASE ANTAGONISTS | INSTITUTO DE MEDICINA MOLECULAR (PT) | 2019-03-14 | — | — | WO | disclosed |