Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 6/20 | 0.73 |
| ▸ | IDO1 | P14902 | 11/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20811355 | 0.90 | NQO1 (0.76) | NQO1IDO1 | |
| SCHEMBL20811039 | 0.90 | NQO1 (0.76) | NQO1IDO1 | |
| SCHEMBL18791172 | 0.84 | NQO1 (1.00) | NQO1IDO1S100A4 | |
| SCHEMBL18791168 | 0.78 | NQO1 (1.00) | NQO1IDO1 | |
| SCHEMBL20811501 | 0.78 | NQO1 (0.59) | NQO1IDO1 | |
| SCHEMBL23406759 | 0.78 | NQO1 (0.59) | NQO1IDO1 | |
| SCHEMBL18791098 | 0.77 | NQO1 (0.67) | NQO1IDO1 | |
| SCHEMBL18791169 | 0.77 | NQO1 (1.00) | NQO1IDO1S100A4 | |
| SCHEMBL103949 | 0.72 | IDO1 (0.53) | NQO1IDO1 | |
| SCHEMBL20811248 | 0.71 | IDO1 (0.59) | NQO1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210161855-A1 | 5-LIPOXYGENASE ANTAGONISTS | Instituto de Medicina Molecular João Lobo Antunes (PT) | 2021-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210161855-A1 | 5-LIPOXYGENASE ANTAGONISTS | ALOX5, ALOX15, ALOX15B | NQO1 85/4885IDO1 342/4885DHODH 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.