Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 13/20 | 0.59 |
| ▸ | NQO1 | P15559 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POR | P16435 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103949 | 0.82 | IDO1 (0.53) | IDO1NQO1KDM4EMEN1CES2 | |
| SCHEMBL18791100 | 0.81 | IDO1 (0.55) | IDO1NQO1KDM4EMEN1CES2 | |
| SCHEMBL29979451 | 0.80 | IDO1 (0.44) | IDO1NQO1KDM4EMEN1CES2 | |
| SCHEMBL18791133 | 0.78 | IDO1 (0.63) | IDO1NQO1KDM4EMEN1CES2 | |
| SCHEMBL20811039 | 0.75 | NQO1 (0.76) | IDO1NQO1KDM4EMEN1CES2 | |
| SCHEMBL3618661 | 0.74 | IDO1 (1.00) | IDO1NQO1KDM4EMEN1CES2 | |
| SCHEMBL10141791 | 0.74 | IDO1 (0.55) | IDO1NQO1KDM4EMEN1CES2 | |
| SCHEMBL18791099 | 0.74 | NQO1 (0.46) | IDO1NQO1KDM4EMEN1CES2 | |
| SCHEMBL20811355 | 0.73 | NQO1 (0.76) | IDO1NQO1MEN1MAPTRAB9A | |
| SCHEMBL23457125 | 0.71 | NQO1 (0.73) | IDO1NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210161855-A1 | 5-LIPOXYGENASE ANTAGONISTS | Instituto de Medicina Molecular João Lobo Antunes (PT) | 2021-06-03 | — | — | US | disclosed |
| WO-2019050422-A1 | 5-LIPOXYGENASE ANTAGONISTS | INSTITUTO DE MEDICINA MOLECULAR (PT) | 2019-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210161855-A1 | 5-LIPOXYGENASE ANTAGONISTS | ALOX5, ALOX15, ALOX15B | IDO1 342/4885NQO1 85/4885KDM4E 1552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.