⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127344 | 0.79 | PPP1R15A (0.46) | — | |
| SCHEMBL5527828 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL5807387 | 0.78 | — | — | |
| SCHEMBL9586694 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL1058814 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL3301954 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL1046503 | 0.75 | ALDH1A1 (0.48) | — | |
| SCHEMBL1046504 | 0.75 | ALDH1A1 (0.48) | — | |
| Water SCHEMBL22130353 | 0.74 | ALDH1A1 (0.59) | — | |
| SCHEMBL575083 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113831272-B | Method for synthesizing 2-substituted indole compound by palladium-catalyzed iodobenzene and oxime ester | 华南理工大学 | 2023-07-18 | — | — | CN | claimed |
| CN-113831272-A | Method for synthesizing 2-substituted indole compound by using palladium to catalyze iodobenzene and oxime ester | 华南理工大学 | 2021-12-24 | — | — | CN | claimed |
| EP-3707231-B1 | ANTI-FOAM COMPOSITIONS | PROCTER & GAMBLE (US) | 2021-12-01 | — | — | EP | claimed |
| EP-3707231-A1 | ANTI-FOAM COMPOSITIONS | The Procter and Gamble Company (US) | 2020-09-16 | — | — | EP | claimed |
| US-8450303-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA, NV (BE) | 2013-05-28 | — | — | US | claimed |
| US-8426401-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA, NV | 2013-04-23 | — | — | US | claimed |
| CN-102459255-A | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2012-05-16 | — | — | CN | claimed |
| CN-102459240-A | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV | 2012-05-16 | — | — | CN | claimed |
| CN-102379872-A | Compounds, compositions and methods of inhibiting a-synuclein toxicity | WHITEHEAD BIOMEDICAL INST | 2012-03-21 | — | — | CN | claimed |
| EP-2421856-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | claimed |
| US-5252686-A | Siloxane polymers and positive working light-sensitive compositions comprising the same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-12 | — | — | US | claimed |
| US-5216105-A | SILICONE POLYMERS AND POSITIVE WORKING LIGHT-SENSITIVE COMPOSITIONS COMPRISING THE SAME | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-01 | — | — | US | claimed |
| EP-0010652-B1 | 4-CHLOROOXAZOLES, METHOD FOR THEIR PREPARATION AND THEIR USE IN PHOTOCONDUCTIVE COATINGS IN ELECTROPHOTOGRAPHY AND AS OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-05-18 | — | — | EP | claimed |
| EP-0048165-A1 | Bis-tetrazolemethyl substituted beta-lactam antibiotics, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | claimed |
| US-4304774-A | Bis-tetrazolmethyl substituted β-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1981-12-08 | — | — | US | claimed |
| US-4182861-A | OPTICAL BRIGHTENERS FOR POLYESTER, COTTON, POLYAMIDE AND POLYACRYLONITRILE FABRICS, POLYVINYL CHLORIDE FOILS | SANDOZ LTD. (CH) | 1980-01-08 | — | — | US | claimed |
| US-4138548-A | Acaricidal pyridinium salts | FISONS LIMITED (GB) | 1979-02-06 | — | — | US | claimed |
| US-4125617-A | Acaricidal pyridinium salts | FISONS LIMITED (GB) | 1978-11-14 | — | — | US | claimed |
| US-4059584-A | ANTIINFLAMMATORY | PFIZER (US) | 1977-11-22 | — | — | US | claimed |
| US-4002623-A | Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines | PFIZER INC. (US) | 1977-01-11 | — | — | US | claimed |