Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 20/20 | 0.73 |
| ▸ | CHEK1 | O14757 | 18/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.73 |
| ▸ | PRKCG | P05129 | 1/20 | 0.73 |
| ▸ | PRKCB | P05771 | 1/20 | 0.73 |
| ▸ | CDK4 | P11802 | 1/20 | 0.73 |
| ▸ | PRKCA | P17252 | 1/20 | 0.73 |
| ▸ | PRKCH | P24723 | 1/20 | 0.73 |
| ▸ | PRKCI | P41743 | 1/20 | 0.73 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.73 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.73 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832547 | 0.85 | WEE1 (0.74) | WEE1CHEK1MEN1PRKD3PRKCG | |
| SCHEMBL6516584 | 0.85 | WEE1 (1.00) | WEE1CHEK1MEN1PRKD3PRKCG | |
| SCHEMBL29414147 | 0.85 | WEE1 (1.00) | WEE1CHEK1MEN1PRKD3PRKCG | |
| SCHEMBL30250020 | 0.85 | WEE1 (1.00) | WEE1CHEK1MEN1PRKD3PRKCG | |
| SCHEMBL5828688 | 0.84 | WEE1 (0.75) | WEE1CHEK1PRKCQ | |
| Water SCHEMBL29521708 | 0.84 | WEE1 (0.97) | WEE1CHEK1MEN1PRKD3PRKCG | |
| SCHEMBL5828095 | 0.82 | WEE1 (1.00) | WEE1CHEK1MEN1PRKD3PRKCG | |
| SCHEMBL5828330 | 0.82 | WEE1 (1.00) | WEE1CHEK1MEN1PRKD3PRKCG | |
| SCHEMBL5829426 | 0.80 | WEE1 (0.66) | WEE1CHEK1MEN1PRKD3PRKCG | |
| SCHEMBL5828696 | 0.79 | WEE1 (1.00) | WEE1CHEK1MEN1PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 Theraprutics, Inc. (US) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190076539-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | GCGR, STUB1, GID4 | WEE1 2564/4885CHEK1 1049/4885MEN1 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.