SCHEMBL20813702

SCHEMBL20813702

Cc1ccc(C#Cc2ccc(-c3ccc4c(F)c(C#CC(F)(F)F)c(F)cc4c3)c(F)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.32
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20813944 0.92
SCHEMBL20803199 0.90 HSD17B1 (0.33) GRM5HSD17B1HSD17B2
SCHEMBL20813653 0.90 CYP11B1 (0.33) HSD17B1HSD17B2
SCHEMBL20813282 0.90 HSD17B1 (0.33) HSD17B1HSD17B2
SCHEMBL20813499 0.89 CA12 (0.31) GRM5
SCHEMBL20813975 0.86
SCHEMBL20803158 0.85 HSD17B1 (0.30) HSD17B1HSD17B2
SCHEMBL20813674 0.84 CYP11B1 (0.31)
SCHEMBL20802466 0.83 GRM5 (0.35) GRM5
SCHEMBL20813648 0.83 PDE9A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3453697-A1 COMPOUND HAVING NAPHTHALENE RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2019-03-13 EP disclosed