Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20830735 | 0.88 | MEN1 (0.47) | CYP1A2CYP2C19LMNAL3MBTL1MEN1 | |
| SCHEMBL20830398 | 0.87 | MEN1 (0.46) | CYP1A2CYP2C19LMNAL3MBTL1MEN1 | |
| SCHEMBL16964861 | 0.87 | CA1 (0.47) | CYP1A2CYP2C19LMNAL3MBTL1MEN1 | |
| SCHEMBL20830399 | 0.87 | CA12 (0.47) | LMNAMEN1RGS12USP2MAPT | |
| SCHEMBL20830748 | 0.87 | MEN1 (0.46) | CYP1A2CYP2C19LMNAL3MBTL1MEN1 | |
| SCHEMBL16965549 | 0.87 | KMT2A (0.61) | CASP3LMNAL3MBTL1MEN1RGS12 | |
| SCHEMBL16965144 | 0.84 | KDM4E (0.55) | CASP3LMNAMEN1RGS12USP2 | |
| SCHEMBL20830510 | 0.84 | APAF1 (0.45) | CYP1A2LMNAMEN1RGS12USP2 | |
| SCHEMBL16965659 | 0.84 | CLTC (0.43) | CYP1A2CYP2C19LMNAL3MBTL1MEN1 | |
| SCHEMBL16965485 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2C19CASP3LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900239-B1 | DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, OCULAR DISEASES AND RELATED DISORDERS | WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC (US) | 2019-03-20 | — | — | EP | disclosed |
| EP-2900239-B1 | DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, OCULAR DISEASES AND RELATED DISORDERS | WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC (US) | 2019-03-20 | — | — | EP | disclosed |