Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.71 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.71 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.71 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.71 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.71 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.71 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.71 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | CASP7 | P55210 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814724 | 1.00 | GPBAR1 (0.71) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL7699066 | 0.88 | GPBAR1 (0.67) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL26753858 | 0.86 | GPBAR1 (0.68) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL1358416 | 0.86 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL28179700 | 0.86 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL25515762 | 0.86 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL7617897 | 0.85 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL20748953 | 0.85 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL14812914 | 0.85 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL19313992 | 0.85 | GPBAR1 (0.73) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11389539-B2 | Hyaluronic acid derivatives into which cationic and hydrophobic groups are introduced | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-07-19 | — | — | US | disclosed |
| US-20220160849-A1 | CANCER VACCINE FORMULATION | MIE UNIVERSITY (JP) | 2022-05-26 | — | — | US | disclosed |
| EP-3919072-A1 | CANCER VACCINE PREPARATION | Mie University (JP) | 2021-12-08 | — | — | EP | disclosed |
| US-20210371548-A1 | HYALURONIC ACID DERIVATIVE MODIFIED WITH POLYETHYLENE GLYCOL | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-12-02 | — | — | US | disclosed |
| EP-3712181-A1 | HYALURONIC ACID DERIVATIVE MODIFIED WITH POLY(ETHYLENE GLYCOL) | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-09-23 | — | — | EP | disclosed |
| US-20190142959-A1 | HYALURONIC ACID DERIVATIVES INTO WHICH CATIONIC AND HYDROPHOBIC GROUPS ARE INTRODUCED | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2019-05-16 | — | — | US | disclosed |
| EP-3456745-A1 | HYALURONIC ACID DERIVATIVE HAVING CATIONIC GROUP AND HYDROPHOBIC GROUP INTRODUCED THEREIN | Chugai Seiyaku Kabushiki Kaisha (JP) | 2019-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11389539-B2 | Hyaluronic acid derivatives into which cationic and hydrophobic groups are introduced | CD44, MUC1, FUT5 | GPBAR1 2485/4885EPHA2 1660/4885HSD17B10 825/4885 |
| US-20210371548-A1 | HYALURONIC ACID DERIVATIVE MODIFIED WITH POLYETHYLENE GLYCOL | CD44, F12, HPSE | GPBAR1 2619/4885EPHA2 1576/4885HSD17B10 574/4885 |
| US-20220160849-A1 | CANCER VACCINE FORMULATION | CD44, TP53, MUC1 | GPBAR1 3817/4885EPHA2 841/4885HSD17B10 768/4885 |
| US-20190142959-A1 | HYALURONIC ACID DERIVATIVES INTO WHICH CATIONIC AND HYDROPHOBIC GROUPS ARE INTRODUCED | CD44, MUC1, FUT5 | GPBAR1 2485/4885EPHA2 1660/4885HSD17B10 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.