Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 4/20 | 1.00 |
| ▸ | MAX | P61244 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.61 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20816067 | 1.00 | MYC (1.00) | MYCMAXALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL17051283 | 0.87 | MYC (0.76) | MYCMAXALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL1124985 | 0.85 | MYC (0.74) | MYCMAXALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL1124983 | 0.85 | MYC (0.74) | MYCMAXALDH1A1SMN1; SMN2DNM1 | |
| SCHEMBL10417660 | 0.81 | PTPN12 (0.73) | MYCMAXALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10417661 | 0.81 | PTPN12 (0.73) | MYCMAXALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL12008740 | 0.79 | MYC (0.83) | MYCMAXALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL12961221 | 0.78 | MYC (1.00) | MYCMAXALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL12008430 | 0.77 | MYC (0.76) | MYCMAXALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8205853 | 0.76 | HSD17B3 (0.62) | MYCMAXALDH1A1SMN1; SMN2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | UNIVERSITY OF ROCHESTER | 2023-07-06 | — | — | US | disclosed |
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | UNIVERSITY OF ROCHESTER | 2023-07-06 | — | — | US | disclosed |
| US-20230190961-A1 | COMPOSITIONS AND METHODS FOR TREATING MYELIN DEFICIENCY BY REJUVENATING GLIAL PROGENITOR CELLS | UNIVERSITY OF ROCHESTER | 2023-06-22 | — | — | US | disclosed |
| US-20230190961-A1 | COMPOSITIONS AND METHODS FOR TREATING MYELIN DEFICIENCY BY REJUVENATING GLIAL PROGENITOR CELLS | UNIVERSITY OF ROCHESTER | 2023-06-22 | — | — | US | disclosed |
| US-20230133695-A1 | METHODS AND COMPOSITIONS FOR REJUVENATING CNS GLIAL POPULATIONS BY SUPPRESION OF TRANSCRIPTION FACTORS | UNIVERSITY OF ROCHESTER | 2023-05-04 | — | — | US | disclosed |
| US-20230133695-A1 | METHODS AND COMPOSITIONS FOR REJUVENATING CNS GLIAL POPULATIONS BY SUPPRESION OF TRANSCRIPTION FACTORS | UNIVERSITY OF ROCHESTER | 2023-05-04 | — | — | US | disclosed |
| US-20190085404-A1 | METHODS OF IDENTIFYING AND TREATING IMMUNE CHECKPOINT INHIBITOR-RESPONSIVE NEOPLASMS AND CELLS, TRANSGENIC ANIMALS AND KITS FOR USE THEREIN | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133695-A1 | METHODS AND COMPOSITIONS FOR REJUVENATING CNS GLIAL POPULATIONS BY SUPPRESION OF TRANSCRIPTION FACTORS | IKZF3, IKZF1, CXXC4 | MYC 19/4885MAX 558/4885ALDH1A1 3617/4885 |
| US-20230190961-A1 | COMPOSITIONS AND METHODS FOR TREATING MYELIN DEFICIENCY BY REJUVENATING GLIAL PROGENITOR CELLS | TEAD2, MYT1, TEAD1 | MYC 32/4885MAX 2012/4885ALDH1A1 3276/4885 |
| US-20230212568-A1 | MICRORNA-MEDIATED METHODS FOR REJUVENATING CNS GLIAL POPULATIONS | MYT1, STAT3, MYC | MYC 3/4885MAX 747/4885ALDH1A1 3434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.