Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367104 | 0.80 | TSHR (0.41) | ALDH1A1TSHRATM | |
| SCHEMBL9615000 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTCYP2D6CYP2C19 | |
| SCHEMBL17222384 | 0.73 | EPHX1 (0.30) | ALDH1A1 | |
| SCHEMBL13219148 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPTCYP2D6CYP2C19 | |
| SCHEMBL1520965 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTCYP2D6CYP2C19 | |
| SCHEMBL1219034 | 0.70 | LMNA (0.41) | ALDH1A1TSHRCYP2D6CYP2C19NPSR1 | |
| SCHEMBL17023657 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTCYP2D6CYP2C19 | |
| SCHEMBL12172112 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTCYP2D6CYP2C19 | |
| SCHEMBL17222426 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL4266774 | 0.69 | EPHX1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111788208-B | Talarstatin analogues | PH制药有限公司 | 2023-11-24 | — | — | CN | disclosed |
| US-11691982-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2023-07-04 | — | — | US | disclosed |
| US-11691982-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2023-07-04 | — | — | US | disclosed |
| US-20200407369-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-12-31 | — | — | US | disclosed |
| US-10815246-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2020-10-27 | — | — | US | disclosed |
| CN-111788208-A | Talanstatin analogs | PH制药有限公司 | 2020-10-16 | — | — | CN | disclosed |
| EP-3684773-A1 | THAILANSTATIN ANALOGS | pH Pharma Co., Ltd. (KR) | 2020-07-29 | — | — | EP | disclosed |
| US-20200216463-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-07-09 | — | — | US | disclosed |
| US-20190233430-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-08-01 | — | — | US | disclosed |
| US-10301319-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2019-05-28 | — | — | US | disclosed |
| WO-2019060398-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-03-28 | — | — | WO | disclosed |
| US-20190084996-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190233430-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | ALDH1A1 2912/4885TSHR 1931/4885ATM 3738/4885 |
| US-10815246-B2 | Thailanstatin analogs | CD47, SUGT1, TPT1 | ALDH1A1 2912/4885TSHR 1931/4885ATM 3738/4885 |
| US-10301319-B2 | Thailanstatin analogs | CD47, SUGT1, TPT1 | ALDH1A1 2912/4885TSHR 1931/4885ATM 3738/4885 |
| US-20200216463-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | ALDH1A1 2912/4885TSHR 1931/4885ATM 3738/4885 |
| US-20200407369-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | ALDH1A1 2912/4885TSHR 1931/4885ATM 3738/4885 |
| US-11691982-B2 | Thailanstatin analogs | CD47, SUGT1, TPT1 | ALDH1A1 2912/4885TSHR 1931/4885ATM 3738/4885 |
| US-20190084996-A1 | THAILANSTATIN ANALOGS | CD47, SUGT1, TPT1 | ALDH1A1 2912/4885TSHR 1931/4885ATM 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.