Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CAD | P27708 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydroorotate SCHEMBL29901858 | 0.85 | CAD (0.43) | MAPTGAAALDH1A1CADHTT | |
| Dihydroorotate SCHEMBL417324 | 0.85 | CAD (0.43) | MAPTGAAALDH1A1CADHTT | |
| Dihydroorotate SCHEMBL121953 | 0.85 | CAD (0.43) | MAPTGAAALDH1A1CADHTT | |
| Dihydroorotate SCHEMBL758070 | 0.85 | CAD (0.43) | MAPTGAAALDH1A1CADHTT | |
| SCHEMBL690090 | 0.71 | — | — | |
| SCHEMBL690089 | 0.71 | — | — | |
| SCHEMBL1300246 | 0.71 | — | — | |
| SCHEMBL16467758 | 0.69 | CAD (0.48) | MAPTGAACADHTTGRIA2 | |
| SCHEMBL6950284 | 0.69 | — | — | |
| SCHEMBL23182639 | 0.69 | CRBN (0.38) | ALDH1A1KDM4ECADUSP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681521-A1 | METABOLOMIC REVISION OF MAMMALIAN INFANTS | Evolve Biosystems Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019055718-A1 | METABOLOMIC REVISION OF MAMMALIAN INFANTS | Evolve Biosystems, Inc. (US) | 2019-03-21 | — | — | WO | disclosed |