Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.68 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.68 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.68 |
| ▸ | CDK2 | P24941 | 3/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922885 | 0.94 | CDK1 (0.71) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL1377647 | 0.88 | CDK1 (0.76) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL22348820 | 0.86 | CCNE1 (0.52) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL3441038 | 0.86 | CDK1 (0.57) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL26218657 | 0.85 | ADORA2A (0.58) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL3441032 | 0.84 | CDK1 (0.59) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL4845463 | 0.84 | CDK1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL4848376 | 0.84 | CDK1 (0.50) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL4849504 | 0.84 | TLR9 (0.51) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL4847394 | 0.84 | HSP90AB1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10231986-B2 | Amino acid phosphoramidate pronucleotides of 2′-cyano, azido and amino nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2019-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10231986-B2 | Amino acid phosphoramidate pronucleotides of 2′-cyano, azido and amino nucleosides for the treatment of HCV | PNP, RNGTT, NSUN2 | CDK1 476/4885CCNB1 704/4885CCNE1 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.