Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 14/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172274 | 0.96 | ADORA2A (0.55) | HSP90AB1HSP90AA1CDK1CCNB1CCNE1 | |
| SCHEMBL2098713 | 0.87 | HSP90AB1 (0.53) | HSP90AB1HSP90AA1 | |
| SCHEMBL24941702 | 0.86 | TK1 (0.60) | HSP90AB1HSP90AA1ADORA2A | |
| SCHEMBL5161283 | 0.85 | HDAC1 (0.49) | CDK1CCNE1CDK2ADORA2ACYP1A2 | |
| SCHEMBL27863480 | 0.84 | HSP90AB1 (0.51) | HSP90AB1HSP90AA1 | |
| SCHEMBL5161068 | 0.84 | HDAC1 (0.51) | CCNE1CDK2ADORA2ACYP1A2 | |
| SCHEMBL20820140 | 0.84 | CDK1 (0.68) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL27854926 | 0.83 | CDK1 (0.71) | HSP90AB1HSP90AA1CDK1CCNB1CCNE1 | |
| SCHEMBL4845463 | 0.83 | CDK1 (0.53) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL4849504 | 0.83 | TLR9 (0.51) | HSP90AB1HSP90AA1CDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321035-B2 | Process for producing 2,6-dihalogenopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-01-22 | — | — | US | disclosed |
| EP-1375502-B1 | PROCESS FOR PRODUCING 2,6-DIHALOGENOPURINE | SUMITOMO CHEMICAL CO (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-6936713-B2 | Process for producing 2,6-dihalogenopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-30 | — | — | US | disclosed |
| US-20050090666-A1 | Process for producing 2,6-dihalogenopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1375502-A1 | PROCESS FOR PRODUCING 2,6-DIHALOGENOPURINE | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 2004-01-02 | — | — | EP | disclosed |
| US-20030144508-A1 | Process for producing 2,6-dihalogenopurine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |