Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.63 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.63 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.63 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.63 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.63 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.63 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.63 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.60 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.60 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.60 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.59 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.59 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.58 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081092 | 1.00 | P2RY1 (0.63) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL20820173 | 0.90 | P2RY1 (0.55) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL16081121 | 0.90 | P2RY1 (0.55) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL20820229 | 0.89 | P2RX1 (0.75) | P2RY1P2RX3P2RX1P2RX4P2RY11 | |
| SCHEMBL15698596 | 0.89 | P2RX1 (0.75) | P2RY1P2RX3P2RX1P2RX4P2RY11 | |
| SCHEMBL18771184 | 0.89 | P2RX1 (0.75) | P2RY1P2RX3P2RX1P2RX4P2RY11 | |
| SCHEMBL29750562 | 0.89 | P2RX1 (0.75) | P2RY1P2RX3P2RX1P2RX4P2RY11 | |
| SCHEMBL18269547 | 0.88 | P2RY1 (0.79) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL3502237 | 0.88 | P2RY1 (0.79) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL625828 | 0.88 | P2RY1 (0.79) | P2RY1P2RX3P2RX1ENPP1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10231986-B2 | Amino acid phosphoramidate pronucleotides of 2′-cyano, azido and amino nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2019-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10231986-B2 | Amino acid phosphoramidate pronucleotides of 2′-cyano, azido and amino nucleosides for the treatment of HCV | PNP, RNGTT, NSUN2 | P2RY1 26/4885P2RX3 145/4885P2RX1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.