SCHEMBL2082246

SCHEMBL2082246

C=CC/C(C(=O)O)=C(\C)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FNTA P49354 2/20 0.42
FNTB P49356 2/20 0.42
THRB P10828 1/20 0.42
PGGT1B P53609 1/20 0.42
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GRIK1 P39086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1135817 1.00 FNTA (0.42) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL11969997 1.00 FNTA (0.42) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL8927707 0.85 FNTA (0.34) FNTAFNTBTHRBPGGT1B
SCHEMBL28268445 0.83 GRIK1 (0.40) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL1644504 0.83 ALDH1A1 (0.35) FNTAFNTBTHRBPGGT1BALDH1A1
SCHEMBL3903875 0.82 LMNA (0.37) ALDH1A1ALOX15HSD17B10
SCHEMBL815175 0.82 LMNA (0.37) ALDH1A1ALOX15HSD17B10
SCHEMBL815174 0.82 LMNA (0.37) ALDH1A1ALOX15HSD17B10
SCHEMBL10901739 0.81 ALDH1A1 (0.33) ALDH1A1GRIK1
SCHEMBL17258210 0.79 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
EP-3861976-B1 DENTAL MATERIALS BASED ON CYCLOPOLYMERISABLE CROSS-LINKING AGENTS IVOCLAR VIVADENT AG (LI) 2022-03-30 EP disclosed
EP-3861976-A1 DENTAL MATERIALS BASED ON CYCLOPOLYMERISABLE CROSS-LINKING AGENTS Ivoclar Vivadent AG (LI) 2021-08-11 EP disclosed
US-9431172-B2 Biaxially oriented electrical insulating film BOREALIS TECHNOLOGY OY (FI) 2016-08-30 US disclosed
US-20150030922-A1 BINDER COMPOSITION FOR SECONDARY BATTERY POSITIVE ELECTRODE, SLURRY COMPOSITION FOR SECONDARY BATTERY POSITIVE ELECTRODE, POSITIVE ELECTRODE, AND SECONDARY BATTERY ZEON CORPORATION (JP) 2015-01-29 US disclosed
US-8163845-B2 Biaxially oriented electrical insulating film TREOFAN GERMANY GMBH & CO. KG (DE) 2012-04-24 US disclosed
EP-1894716-B1 Biaxially oriented, electrically insulating film TREOFAN GERMANY GMBH & CO KG (DE) 2010-11-10 EP disclosed
EP-1894715-B1 Biaxially oriented, electrically insulating film TREOFAN GERMANY GMBH & CO KG (DE) 2010-07-28 EP disclosed
US-20100047544-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2010-02-25 US disclosed
US-20100003489-A1 BIAXIALLY ORIENTED ELECTRICAL INSULATING FILM TREOFAN GERMANY GMBH & CO. KG (DE) 2010-01-07 US disclosed
EP-0964011-A1 Polyolefine graft copolymers Borealis AG (AT) 1999-12-15 EP disclosed
EP-0891989-A1 Modified polymers containing methylene groups PCD Polymere AG (AT) 1999-01-20 EP disclosed
EP-0884355-A1 Polyolefin foams with fine cells PCD Polymere AG (AT) 1998-12-16 EP disclosed
EP-0879844-A1 Polyolefin foams with high resistance against deformation by heat PCD Polymere AG (AT) 1998-11-25 EP disclosed
EP-0879830-A1 Modified polypropylene having improved processability PCD Polymere AG (AT) 1998-11-25 EP disclosed
EP-0878567-A2 Polyolefin fibres and polyolefin yarns and textile materials thereof PCD Polymere AG (AT) 1998-11-18 EP disclosed
EP-0821018-A2 Crosslinkable olefinic polymers and method for their preparation PCD-Polymere Gesellschaft m.b.H. (AT) 1998-01-28 EP disclosed
EP-0792905-A2 Continuous process for preparing polypropylene compositions with improved stress crack resistance and high melt strength PCD-Polymere Gesellschaft m.b.H. (AT) 1997-09-03 EP disclosed
EP-0792894-A2 Continuous modification of polyolefins in solid phase PCD-Polymere Gesellschaft m.b.H. (AT) 1997-09-03 EP disclosed
EP-0787750-A2 Poly(alkylethylene) structural isomers PCD-Polymere Gesellschaft m.b.H. (AT) 1997-08-06 EP disclosed