⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484508 | 0.69 | — | — | |
| SCHEMBL9536696 | 0.69 | — | — | |
| SCHEMBL16047897 | 0.69 | — | — | |
| SCHEMBL48038 | 0.69 | — | — | |
| SCHEMBL7291155 | 0.67 | — | — | |
| SCHEMBL4650378 | 0.67 | — | — | |
| SCHEMBL3050586 | 0.67 | — | — | |
| SCHEMBL6448015 | 0.65 | — | — | |
| SCHEMBL208497 | 0.65 | — | — | |
| SCHEMBL14403788 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492536-B1 | 4-(N-PHENYLAMINO)-QUINAZOLINES / QUINOLINES AS TYROSINE KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2012-05-09 | — | — | EP | claimed |
| EP-2298305-A1 | 4-(N-Phenylamino)-quinazolines/quinolines as inhibitors of tyrosine kinases | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2011-03-23 | — | — | EP | claimed |
| EP-2056897-B1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES B V (NL) | 2009-12-30 | — | — | EP | claimed |
| US-7456189-B2 | Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-25 | — | — | US | claimed |
| US-20070004765-A1 | New compounds | BIOVITRUM AB (SE) | 2007-01-04 | — | — | US | claimed |
| WO-2006122931-A1 | BETA-CARBOLINE DERIVATIVES AND THERI USE AS GHSR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2006-11-23 | — | — | WO | claimed |
| US-7119084-B2 | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-10-10 | — | — | US | claimed |
| US-20060094710-A1 | Piperidine-pyridazones and phthalazones as pde4 inhibitors | ALTANA PHARMA AG (DE) | 2006-05-04 | — | — | US | claimed |
| US-20050288316-A1 | Beta-carbolines as growth hormone secretagogue receptor (GHSR) antagonists | BIOVITRUM AB (SE) | 2005-12-29 | — | — | US | claimed |
| US-20050182043-A1 | Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-18 | — | — | US | claimed |
| EP-0158057-A1 | Salts of oxazaphosphorine derivatives | ASTA Pharma AG (DE) | 1985-10-16 | — | — | EP | claimed |
| US-4342769-A | 2-[(Methylsulfinyl)acetyl]-3-heterocyclicindoles and derivatives thereof as immunosuppressants | SCHERING CORPORATION (US) | 1982-08-03 | — | — | US | claimed |
| US-4328345-A | Pyridyl substituted indoles | SCHERING CORPORATION (US) | 1982-05-04 | — | — | US | claimed |
| US-4256752-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-03-17 | — | — | US | claimed |
| US-4255442-A | 2-[(Methylsulfinyl)]-3-phenylindoles | SCHERING CORPORATION (US) | 1981-03-10 | — | — | US | claimed |
| EP-0000645-B1 | ISOPENICILLINS, PROCESSES FOR THEIR PREPARATION, AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-01-28 | — | — | EP | claimed |
| US-4225711-A | Substituted 2-[(methylsulfinyl)acetyl]-3-heterocyclicindoles and their use as immunosuppressants | SCHERING CORPORATION (US) | 1980-09-30 | — | — | US | claimed |
| US-4144333-A | Monocyclic beta-lactams with antibacterial activity | SMITHKLINE CORPORATION (US) | 1979-03-13 | — | — | US | claimed |
| EP-0000645-A1 | Isopenicillins, processes for their preparation, and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-02-07 | — | — | EP | claimed |
| US-4122086-A | Isopenicillins | SMITHKLINE CORPORATION (US) | 1978-10-24 | — | — | US | claimed |