⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28209845 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL3411438 | 0.71 | — | — | |
| SCHEMBL2051138 | 0.71 | — | — | |
| SCHEMBL208235 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL28143788 | 0.69 | ALDH1A1 (0.37) | — | |
| SCHEMBL11401125 | 0.69 | — | — | |
| Fluoride SCHEMBL28143708 | 0.69 | — | — | |
| SCHEMBL11583271 | 0.69 | — | — | |
| SCHEMBL10493368 | 0.69 | KDM4E (0.36) | — | |
| SCHEMBL79143 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101854957-B | radiofluorination method | GE HEALTHCARE LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-101854957-A | radiofluorination method | GE HEALTHCARE LTD | 2010-10-06 | — | — | CN | disclosed |
| CN-101321519-A | Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom | ILYPSA INC (US) | 2008-12-10 | — | — | CN | disclosed |
| CN-101316601-A | Methods and compositions for selective removal of potassium ions from the gastrointestinal tract of a mammal | ILYPSA INC (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-1097417-A | New heterogeneous ring compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-18 | — | — | CN | disclosed |
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |
| EP-0273369-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |