Sugi Predict

Sugi Predict / Compounds / SCHEMBL20823914

SCHEMBL20823914

SCHEMBL20823914

c1ccc(N(c2ccc3c(c2)-c2ccccc2C32c3ccccc3Oc3ccccc32)c2ccc3c(c2)C2(c4ccccc4Oc4ccccc42)c2ccccc2-3)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 2/20 0.36
▸ MAPT P10636 3/20 0.34
▸ CYP2C19 P33261 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ KDM4E B2RXH2 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ FTO Q9C0B1 2/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ HPGD P15428 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ RECQL P46063 1/20 0.32
▸ BLM P54132 1/20 0.32
▸ SMAD3 P84022 1/20 0.32
▸ PRMT1 Q99873 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24646468 0.96 PDK2 (0.38) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL24622507 0.96 PDK2 (0.38) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL20823271 0.96 PDK2 (0.38) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL20824492 0.96 PDK2 (0.35) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL20823377 0.96 MAPT (0.37) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL20822748 0.96 PDK2 (0.35) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL20824090 0.96 PDK2 (0.35) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL20822689 0.96 PDK2 (0.35) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL24646876 0.95 KDM4E (0.37) PDK2MAPTCYP2C19TDP1KDM4E
SCHEMBL20823891 0.94 PDK2 (0.35) PDK2MAPTCYP2C19TDP1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3663288-B1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO (JP) 2022-06-08 — — EP disclosed
EP-3663288-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE Idemitsu Kosan Co., Ltd (JP) 2020-06-10 — — EP disclosed
US-10424740-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-09-24 — — US disclosed
US-20190088879-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2019-03-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190088879-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICES, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM PDK2 2623/4885MAPT 2451/4885CYP2C19 1247/4885
US-10424740-B2 Compound, material for organic electroluminescence devices, organic electroluminescence device, and electronic device PIEZO1, LEF1, L1CAM PDK2 2623/4885MAPT 2451/4885CYP2C19 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.