Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745028 | 0.84 | EPHX1 (0.49) | SMN1; SMN2TP53EPHX1EPHX2PTPN1 | |
| SCHEMBL1285838 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53PPIDEPHX1MAPT | |
| SCHEMBL23804482 | 0.79 | EPHX1 (0.44) | SMN1; SMN2TP53EPHX1ALDH1A1EPHX2 | |
| SCHEMBL631833 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2TP53EPHX1MAPTALDH1A1 | |
| SCHEMBL13745043 | 0.77 | RAB9A (0.55) | SMN1; SMN2TP53MAPTALDH1A1L3MBTL1 | |
| SCHEMBL10583653 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2TP53PPIDEPHX1MAPT | |
| SCHEMBL11270405 | 0.72 | EPHX1 (0.62) | SMN1; SMN2TP53PPIDEPHX1MAPT | |
| SCHEMBL6033584 | 0.72 | TP53 (0.75) | SMN1; SMN2TP53EPHX1MAPTALDH1A1 | |
| SCHEMBL714625 | 0.72 | EPHX1 (0.77) | SMN1; SMN2TP53PPIDEPHX1ALDH1A1 | |
| SCHEMBL11262217 | 0.72 | TP53 (0.64) | SMN1; SMN2TP53PPIDEPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |