Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610101 | 0.84 | GAA (0.66) | ALDH1A1GAAMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL2695688 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL1812216 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL8288448 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL1286082 | 0.81 | GAA (0.62) | ALDH1A1GAAMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL25094969 | 0.81 | ALDH1A1 (0.67) | ALDH1A1GAAMAPTHSD17B10MMP13 | |
| SCHEMBL9329665 | 0.81 | ALDH1A1 (0.62) | ALDH1A1GAAMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL6366481 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GAAMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL20825050 | 0.80 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTHSD17B10MMP13 | |
| SCHEMBL7037785 | 0.80 | GAA (0.66) | ALDH1A1GAAMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |