SCHEMBL20825124

SCHEMBL20825124

CC1C=C(CNC=O)C=CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH7 P40394 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24177624 0.78 NCF1 (0.32)
SCHEMBL8304846 0.77
SCHEMBL20663213 0.75 KMT2A (0.33)
SCHEMBL11956867 0.75 ALDH1A1 (0.32)
SCHEMBL20825022 0.73 CYP2C9 (0.34)
SCHEMBL8189444 0.71
SCHEMBL21303913 0.71 HDAC6 (0.37)
SCHEMBL13149528 0.70
SCHEMBL12654339 0.70
SCHEMBL14294916 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427451-B1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BIOLAB CO LTD (JP) 2019-03-20 EP disclosed