Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LOX | P28300 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20811392 | 0.82 | LOX (0.52) | LOX | |
| SCHEMBL20811391 | 0.82 | UBE2N (0.48) | UBE2N | |
| SCHEMBL20811286 | 0.80 | TDP1 (0.55) | UBE2NALDH1A1LOXLMNATSHR | |
| SCHEMBL24653151 | 0.79 | ALDH1A1 (0.47) | UBE2NALDH1A1LOXGAA | |
| SCHEMBL20811393 | 0.79 | LOX (0.52) | ALDH1A1LOXLMNA | |
| SCHEMBL20791549 | 0.79 | ALDH1A1 (0.46) | UBE2NALDH1A1GAALMNA | |
| SCHEMBL20826522 | 0.76 | LOX (0.51) | LOX | |
| SCHEMBL20826067 | 0.75 | HPGD (0.55) | GAAHTT | |
| SCHEMBL20791554 | 0.74 | MAPT (0.67) | ALDH1A1GAALMNATSHRHTT | |
| SCHEMBL20790942 | 0.73 | CA2 (0.58) | ALDH1A1LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055590-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. (US) | 2019-03-21 | — | — | WO | disclosed |