Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3179287 | 1.00 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL20828187 | 0.95 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL3179208 | 0.83 | HIF1A (0.66) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL2141545 | 0.82 | SLC6A3 (0.60) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3184955 | 0.82 | HIF1A (0.60) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL3442705 | 0.82 | HIF1A (0.60) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL4776070 | 0.82 | HIF1A (0.60) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL4776066 | 0.82 | HIF1A (0.60) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL2142477 | 0.81 | SLC6A3 (0.56) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11408759 | 0.81 | SLC6A2 (0.69) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019053425-A1 | BETA-HYDROXY HETEROCYCLIC AMINES AND THEIR USE IN THE TREATMENT OF HYPERGLYCAEMIA | ATROGI AB (SE) | 2019-03-21 | — | — | WO | disclosed |