Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776070 | 1.00 | HIF1A (0.60) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3179208 | 0.83 | HIF1A (0.66) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28886331 | 0.82 | SLC6A3 (0.58) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3442705 | 0.82 | HIF1A (0.60) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL20828152 | 0.82 | SLC6A2 (0.64) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3179287 | 0.82 | SLC6A2 (0.64) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3184955 | 0.82 | HIF1A (0.60) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3174744 | 0.81 | HIF1A (0.62) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1794708 | 0.80 | SLC6A3 (0.62) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL1533285 | 0.80 | SLC6A3 (0.62) | HIF1AHSD17B10SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |