Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 17/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15725187 | 0.91 | GLS (0.66) | GLSMAPT | |
| SCHEMBL20828348 | 0.91 | GLS (0.66) | GLSMAPT | |
| SCHEMBL15725195 | 0.84 | GLS (0.70) | GLSMAPTMEN1KMT2A | |
| SCHEMBL15725186 | 0.84 | GLS (0.70) | GLSMAPTMEN1KMT2A | |
| SCHEMBL20828320 | 0.84 | GLS (0.70) | GLSMAPTMEN1KMT2A | |
| SCHEMBL15725189 | 0.81 | GLS (0.66) | GLSMAPTMEN1KMT2A | |
| SCHEMBL15725188 | 0.81 | GLS (0.66) | GLSMAPTMEN1KMT2A | |
| SCHEMBL15725165 | 0.80 | GLS (0.70) | GLSMEN1KMT2A | |
| SCHEMBL20392384 | 0.80 | GLS (0.70) | GLSMEN1KMT2A | |
| SCHEMBL15725197 | 0.80 | GLS (0.73) | GLSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456719-A1 | COMPOUNDS AND THEIR METHODS OF USE | Agios Pharmaceuticals, Inc. (US) | 2019-03-20 | — | — | EP | disclosed |