Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602662 | 0.88 | L3MBTL1 (0.50) | L3MBTL1MAOBMAOALMNAPKM | |
| SCHEMBL20832626 | 0.88 | L3MBTL1 (0.50) | L3MBTL1MAOBMAOALMNAPKM | |
| SCHEMBL20832811 | 0.84 | L3MBTL1 (0.50) | L3MBTL1MAOBMAOALMNAPKM | |
| SCHEMBL30602686 | 0.84 | L3MBTL1 (0.50) | L3MBTL1MAOBMAOALMNAPKM | |
| SCHEMBL20828518 | 0.81 | L3MBTL1 (0.47) | L3MBTL1MAOBMAOALMNAPKM | |
| SCHEMBL22623097 | 0.80 | L3MBTL1 (0.57) | L3MBTL1MAOBMAOALMNAPKM | |
| SCHEMBL20828440 | 0.79 | MAOA (0.42) | L3MBTL1MAOBMAOAHTR2CPPARG | |
| SCHEMBL20832632 | 0.79 | L3MBTL1 (0.45) | L3MBTL1MAOBMAOALMNAPKM | |
| SCHEMBL22227863 | 0.79 | PPARG (0.48) | L3MBTL1MAOBMAOALMNAHTR2C | |
| SCHEMBL30602660 | 0.79 | L3MBTL1 (0.45) | L3MBTL1MAOBMAOALMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019054430-A1 | AMIDE COMPOUND HAVING AROMATIC HETEROCYCLE | 第一三共株式会社 | 2019-03-21 | — | — | WO | disclosed |