Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22010959 | 0.82 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL18351315 | 0.78 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL12366431 | 0.78 | RIPK1 (0.35) | RIPK1 | |
| SCHEMBL19160558 | 0.78 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL3178175 | 0.77 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL16772345 | 0.76 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL9406055 | 0.75 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL9406059 | 0.75 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL22011817 | 0.75 | RIPK1 (0.30) | RIPK1 | |
| SCHEMBL22010791 | 0.75 | RIPK1 (0.30) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019052973-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-03-21 | — | — | WO | disclosed |