SCHEMBL2082909

SCHEMBL2082909

CCOC(=O)C=CC=Cc1ccc(OC)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
FBP1 P09467 1/20 0.45
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 3/20 0.44
HPGD P15428 2/20 0.44
MAOB P27338 2/20 0.44
LMNA P02545 1/20 0.43
LY96 Q9Y6Y9 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2082907 1.00 MAPT (0.47) MAPTMEN1KMT2AFBP1ALDH1A1
SCHEMBL10669864 0.87 MAPT (0.61) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL10669860 0.87 MAPT (0.61) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL2081608 0.85 MAPT (0.53) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL2081607 0.85 MAPT (0.53) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL15163803 0.83 JUN (0.59) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL12784443 0.82 MAPT (0.50) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL2079001 0.82 MAPT (0.50) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL2079003 0.82 MAPT (0.50) MAPTMEN1KMT2AALDH1A1KDM4E
SCHEMBL12784329 0.81 MAOB (0.49) MAPTMEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897601-B2 Cannabinoid receptor modulators INTERVET, INC. (US) 2011-03-01 US disclosed
EP-1973877-A2 CANNIBINOID RECEPTOR MODULATORS SCHERING CORPORATION (US) 2008-10-01 EP disclosed
US-20070197628-A1 Cannabinoid receptor modulators INTERVET INTERNATIONAL B.V. (NL) 2007-08-23 US disclosed
WO-2007084450-A2 CANNIBINOID RECEPTOR MODULATORS SCHERING CORPORATION (US) 2007-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197628-A1 Cannabinoid receptor modulators CNR1, CNR2, GPR18 MAPT 1582/4885MEN1 4042/4885KMT2A 1524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.