SCHEMBL20829148

SCHEMBL20829148

CC1(C)C=CC=C(c2cc(-c3ccccc3)cc(-c3ccccc3)n2)C=C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.40
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
ADORA1 P30542 2/20 0.38
ADORA3 P0DMS8 1/20 0.38
ADORA2B P29275 1/20 0.38
MYC P01106 1/20 0.36
MAPT P10636 2/20 0.35
TSHR P16473 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RAB9A P51151 2/20 0.34
ALDH1A1 P00352 2/20 0.34
ADORA2A P29274 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LTB4R Q15722 7/20 0.34
MCL1 Q07820 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22212825 0.87 KMT2A (0.40) MEN1KMT2AADORA1MAPTTSHR
SCHEMBL20829149 0.86 MEN1 (0.40) CYP19A1MEN1KMT2AADORA1ADORA3
SCHEMBL21972972 0.85 MEN1 (0.40) MEN1KMT2AADORA1ADORA3MAPT
SCHEMBL20829146 0.77 ADORA2A (0.38) CYP19A1MEN1KMT2AADORA1MAPT
SCHEMBL20829147 0.75 MEN1 (0.45) MEN1KMT2AADORA1ADORA3MAPT
SCHEMBL22072005 0.73
SCHEMBL960513 0.72 CYP19A1 (0.65) CYP19A1MEN1KMT2AADORA1ADORA3
SCHEMBL22296632 0.71 L3MBTL1 (0.54) MEN1KMT2AADORA1ADORA3ADORA2B
SCHEMBL20829145 0.71 ADORA2A (0.41) MEN1KMT2AADORA1MAPTTSHR
SCHEMBL13203192 0.70 CYP19A1 (0.63) CYP19A1MEN1KMT2AADORA1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3197982-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-05-06 EP disclosed
WO-2019052933-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-03-21 WO disclosed