SCHEMBL20829883

SCHEMBL20829883

CCn1c(C(F)(F)F)cc2nc(-c3ccc(C(C)(C)C#N)cc3S(=O)(=O)CC)n(C)c2c1=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 16/20 0.35
S1PR1 P21453 2/20 0.31
ADORA2A P29274 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20104477 0.88 DDR1 (0.33) DDR1
SCHEMBL31248466 0.88 DDR1 (0.33) DDR1
SCHEMBL20829888 0.86 DDR1 (0.33) DDR1
SCHEMBL20829799 0.85 DDR1 (0.33) DDR1
SCHEMBL17539312 0.82 DDR1 (0.40) DDR1
SCHEMBL18073405 0.82 DDR1 (0.36) DDR1ADORA2A
SCHEMBL20829886 0.79 DDR1 (0.31) DDR1
SCHEMBL29787146 0.79 DDR1 (0.31) DDR1
SCHEMBL20505611 0.79 DDR1 (0.35) DDR1S1PR1
SCHEMBL18050182 0.78 DDR1 (0.37) DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3684768-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2024-01-24 EP disclosed
EP-3684768-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2024-01-24 EP disclosed
US-11413291-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2022-08-16 US disclosed
US-20200268760-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2020-08-27 US disclosed
WO-2019053182-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2019-03-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11413291-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents DDT, ACHE, SQOR DDR1 4459/4885S1PR1 2950/4885ADORA2A 3859/4885
US-20200268760-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, ACHE, SQOR DDR1 4459/4885S1PR1 2950/4885ADORA2A 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.