SCHEMBL20829941

SCHEMBL20829941

CSCC(=O)NCCCCCN

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 3/20 0.57
SLC6A5 Q9Y345 2/20 0.47
HIF1A Q16665 2/20 0.44
KDM4A O75164 1/20 0.44
TET2 Q6N021 1/20 0.44
DOHH Q9BU89 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GNAI3 P08754 1/20 0.42
GNAO1 P09471 1/20 0.42
GNAI1 P63096 1/20 0.42
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
CASP2 P42575 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17010827 0.91 PAOX (0.47) PAOXSLC6A5SMN1; SMN2MEN1KMT2A
SCHEMBL10104241 0.83 KMT2A (0.48) HIF1ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL12360826 0.82 CASP2 (0.62) MEN1KMT2ACASP2NAAA
SCHEMBL22931711 0.82 MEN1 (0.45) PAOXHIF1AKDM4ASMN1; SMN2MEN1
SCHEMBL5238610 0.81 PAOX (0.58) PAOXSLC6A5HIF1AKDM4ATET2
SCHEMBL12584161 0.81 PAOX (0.53) PAOXSLC6A5HIF1AKDM4ATET2
SCHEMBL22931570 0.81 PAOX (0.53) PAOXSLC6A5HIF1AKDM4ATET2
SCHEMBL18827287 0.81 PAOX (0.52) PAOXSLC6A5HIF1AKDM4ATET2
SCHEMBL20829925 0.79 SLC6A5 (0.57) PAOXSLC6A5HIF1AKDM4ATET2
SCHEMBL7478566 0.78 MEN1 (0.74) PAOXSLC6A5HIF1AKDM4ATET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3240573-B1 ENZYMATIC CONJUGATION OF POLYPEPTIDES INNATE PHARMA (FR) 2019-03-20 EP disclosed