Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 3/20 | 0.39 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977518 | 0.79 | KMT2A (0.59) | KMT2AHDAC1HDAC6LSSALDH1A1 | |
| SCHEMBL12522662 | 0.75 | KMT2A (0.46) | KMT2AHDAC1HDAC6CYP2C9ALOX15 | |
| SCHEMBL14533961 | 0.75 | KMT2A (0.44) | KMT2AHDAC1HDAC6ALDH1A1MAPT | |
| SCHEMBL18630144 | 0.73 | ALDH1A1 (0.49) | KMT2AHDAC1HDAC6HSD17B10ALDH1A1 | |
| SCHEMBL11955054 | 0.72 | HRH3 (0.43) | KMT2ACYP2C9ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL11049304 | 0.72 | BACE1 (0.58) | KMT2ACYP2C9ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL14651452 | 0.71 | SETDB1 (0.54) | KMT2ASETDB1ALDH1A1RAB9AHTT | |
| SCHEMBL28217034 | 0.70 | HRH3 (0.54) | KMT2ACYP2C9ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL17123629 | 0.70 | KMT2A (0.45) | KMT2AHDAC1HDAC6HSD17B10SETDB1 | |
| SCHEMBL11193465 | 0.70 | NQO2 (0.48) | KMT2AALDH1A1MAPTPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456713-A1 | PROCESS FOR THE PREPARATION OF TRIAZINE DERIVATIVES | Japan Tobacco Inc. (JP) | 2019-03-20 | — | — | EP | disclosed |